We next evaluated cardiac myocyte apoptosis in BO mice with/without Cap treatment by means of terminal deoxyribonucleotidyl transferase (TdT)-mediated biotin-16-deoxyuridine triphosphate (dUTP) nick-end labeling (TUNEL) (Fig. 4A). The gene discussed is DNTT; the disease is bronchiolitis obliterans syndrome.