CD8A and colorectal carcinoma: The top 5 most enriched subpopulations in MSS CRC were CD8+ T central-memory, CD8+ T naive-inflamed, IL17AHIGH MAITs, TOXHIGHCD8+ T memory-exhausted and MAIT-like activated (Fig. 1d), aligning with the known mixed inflammatory phenotypes of MSS CRC1,18.