While the role of TGFβ signaling in cancer initiation, progression, and metastasis is multifaceted and context-dependent (Zhao et al., 2018; Batlle and Massague, 2019), its contribution to the establishment of an immunosuppressive tumor microenvironment has been extensively documented for both adaptive and innate immune responses (Zhao et al., 2018; Batlle and Massague, 2019). Here, TGFB1 is linked to cancer.