SLC26A9 and cystic fibrosis: SLC26A9 has been reported to be physically linked to CFTR through its STAS domain (33), and when expressed together with the CFTR mutant, F508del-CFTR, it is quickly degraded and therefore not expressed at the plasma membrane in CF cells, while in the presence of G551D-CFTR it manifests a normal trafficking phenotype (34).