Nevertheless, the resulting ASL pH in IL-4-treated CF-CTRL epithelia was significantly lower (P < 0.05) compared to IL-4-treated CF-T16AKO epithelia (6.5 ± 0.4 versus 6.8 ± 0.5, n = 27, respectively, Fig. 2E. This evidence concerns the gene IL4 and cystic fibrosis.