Our framework identified 20 potential schizophrenia risk genes: EYA3, CNTN4, HSPA8, LRRK2, AFP, CTNNB1, CYP1A1, FGFR1, PRKAR2A, HTT, SLIT1, MEPCE, CENPC, NDUFA13, PDE4D, PIEZO1, PACSIN2, GSPT1, LOXL2, and CD2AP. Given these results, it is promising to examine what our framework produced. This evidence concerns the gene AFP and schizophrenia.