Cells positive for NRP1 (NRP1med and NRP1hi cells) or IGF1R (IGF1Rmed and IGF1Rhi cells) and cells positive for FXYD3 (FXYD3med and FXYD3hi cells) were more abundant among P3 patient-derived cancer cells than in P6 and P1 patient-derived cells, respectively (Supplemental Figure 10A). The gene discussed is NRP1; the disease is cancer.