NC525-mediated AML suppression was observed across multiple donors and AML subtypes, including normal-karyotype AML, monocytic AML, acute myelomonocytic leukemia (AMML), FLT3-ITD+ AML, and uncharacterized AML (Figure 3B). The gene discussed is FLT3; the disease is acute myelomonocytic leukemia M4.