Given that myeloid cells, predominantly macrophages, mediate long‐term hematoma resolution, neuroinflammation, and neurobehavioral recovery after ICH (Zhao et al, 2017; Askenase et al, 2021; Chang et al, 2021), HSD might impact long‐term stroke outcomes through regulating macrophage functions. The gene discussed is CHST3; the disease is Stroke.