Cytobank‐based viSNE analysis of CyTOF data revealed a complex cellular landscape of cancer cells, immunocytes and other cells in which significant disparity in the distribution of myeloid lineage subtypes was detected among 12 xenografts harbouring different genetic features on the PIK3CA gene, including ‘wild type (wt)’, ‘E545K’ and ‘H1047R’ (Figure 2C). The gene discussed is PIK3CA; the disease is cancer.