As it functions in breast cancer, hepatitis B X-interacting protein (HBXIP) could positively regulate METTL3 levels in GC cells, where METTL3 could interact with the oncogene MYC to increase m6A deposition, promoting proliferation, invasion, and metastasis (Yang et al., 2020a). This evidence concerns the gene METTL3 and breast carcinoma.