STING1 and neuroblastoma: Wang-Bishop et al. researchers mediated effective cytoplasmic delivery of the endogenous STING ligand cGAMP via intratumoral nanoparticle delivery, which enhanced STING activation relative to free cGAMP and improved response to PD-L1 immune checkpoint blockade, inducing immunogenic death in neuroblastoma (Wang-Bishop et al., 2020).