Given that FUCA1, SLC16A12, CYFIP2, and LIMCH1 are lowly expressed in ccRCC tissues and that low expression of the four genes has a worse clinical prognosis, we further validated the expression of FUCA1, SLC16A12, CYFIP2, and LIMCH1 mRNA levels in 10 pairs of paired ccRCC and matched adjacent tissues. Here, CYFIP2 is linked to nonpapillary renal cell carcinoma.