Figure 2B presented the correlations between all these cuproptosis-related genes. Then, to investigate enriched functions associated with cuproptosis-related genes, the hallmark gene set was used for enrichment analysis based on DEGs between two clusters (Figure 2C). In addition, GO and KEGG analysis were also conducted and the results showed the top 5 enriched terms were pathway in cancer, focal adhesion, neurotrophin signaling pathway, neuroactive ligand receptor interaction, and gap junction (Figures 2D, E). This evidence concerns the gene BDNF and cancer.