A likely pathogenic variant was present in another non-MMR gene, MUTYH (NM_001128425.2); c.1476 + 2C>T, in patient 24, where the patient presented with polyps and right-sided tumor that spread to the liver, which is consistent with a polyposis (or MUTYH) associated CRC. This evidence concerns the gene MRC1 and colorectal carcinoma.