These include APC for familial adenomatous polyposis (FAP); BMPR1A and SMAD4 for Juvenile Polyposis Syndrome (JPS); MUTYH for MUTYH-associated polyposis; PTEN for PTEN tumor/hamartoma syndrome (or Cowden syndrome/Bannayan–Riley–Ruvalcaba syndrome); and STK11 for Peutz–Jeghers syndrome. This evidence concerns the gene PTEN and juvenile polyposis syndrome.