Our analysis of OS revealed that higher AURKA expression was associated with worse prognoses in most cancers, including ACC, ESCA, LGG, PCPG, THCA, BLCA, LIHC, PRAD, THYM, BRCA, HNSC, LUAD, UCEC, KICH, LUSC, SARC, KIRC, MESO, SKCM, UVM, KIRP, and PAAD (all p<0.05), as shown in Supplementary Figure 1A. The gene discussed is AURKA; the disease is cancer.