The paper concluded the results of the interactions of twenty-five microRNAs with FOXO3a in malignant tumours such as breast, liver, gastric, colorectal, and prostate cancers: There were dual microRNAs synergizing with FOXO3a to restrain the growth of breast cancer cells miR-29b, miR-338, and miR-34b, miR-34c; and a single microRNA synergizing with FOXO3a to suppress hepatocellular carcinoma cells, such as miR-30b-5p, miR-124-3p.1, and miR-498 (Figure 3A), the tumour suppressor function of these microRNAs makes it possible to be the target of drugs for cancer therapy. Here, FOXO3 is linked to cancer.