miR-155 has been documented as an oncogene in a variety of cancers, and the level FOXO3a, a candidate target of miR-155, was significantly reduced in colorectal cancer cell lines resistant to radiation therapy, while the miR-155 content was significantly elevated; thus, a clear negative correlation between miR-155 and FOXO3a gene expression was identified (56).MiR-96 is upregulated in colorectal cancer and promotes cell growth and proliferation, thus functioning as an oncogene. The gene discussed is FOXO3; the disease is colorectal cancer.