Although the first report of food allergy immunotherapy for eggs dates back more than a century, only small case reports on the use of oral immunotherapy (OIT) appeared sporadically in the literature until 1998, when Patriarca et al. published the first in a series of reports demonstrating that a protocol of oral therapy could be effective in desensitizing children with immunoglobulin E (IgE)-mediated food allergy (1, 2). Here, IGHE is linked to food allergy.