Interestingly, OESO_0105, OESO_0120 and OESO_6518 were non-MPRs, raising the possibility that reduced or dysfunctional T cells responses to tumour antigens or low CD8+ T cell infiltration may be associated with failure to respond to NAT in OAC; however, this requires further testing in a larger cohort of samples. The gene discussed is BRD2; the disease is neoplasm.