Another study identified two myeloperoxidase-derived HLA-A2-restricted peptides (MY4 and MY8) that are immunogenic, and MY4- and MY8-specific cytotoxic T lymphocytes may play a role in reducing leukemia; this indicates that MY4 and MY8 may be novel leukemia-associated antigens for immunotherapy in myeloid leukemia [17]. Here, MPO is linked to leukemia.