This retrospective analysis is consistent with previous reports that D-dimer, leukocyte count, neutrophil count, CRP, and SAA indicate a high risk of severe illness and poor prognosis of COVID-19 (Chen et al., 2020; Li H. et al., 2020; Qin et al., 2020; Wang et al., 2020; Zhou et al., 2020). The gene discussed is CRP; the disease is COVID-19.