IFNG and infection: Since a subset of Tregs can also produce IFNγ (Miyara et al., 2009; Zhao et al., 2011; Koenecke et al., 2012; Sumida et al., 2018), it is interesting to note that mice that received Tregs from either air- or CS-exposed mice had similar number of donor (Thy1.1) IFNγ+ Tregs at Days 1 and 30 after infection, and yet mice that received Tregs from CS-exposed mice had decreased number of donor IFNγ+ Tregs at Day 60 compared to those that received Tregs from air-exposed mice (Figure 9E).