IL10 and infection: While both human cell and murine adoptive studies showed similar relative CFU findings with CS extract- vs. whole CS-exposed Tregs, some differences were observed in the ancillary findings; e.g., whereas unexposed Tregs + macrophages and especially CS-exposed Tregs + macrophages produced significantly more IL-10 than macrophages alone in the human cell studies (Figures 4B, 5D), there was a decrease in IL-10+ macrophages at Day 60 after infection in mice that received Tregs from either unexposed or CS-exposed donor mice (Figure 7E).