As expected, CD133+ or CD90+ RCC cells displayed significantly high CD44, Sox2, Oct4, Nanog, and ALDH1 expresion than CD133- or CD90− RCC cells, indcating that CD133+ or CD90+ RCC cells existed Renal cell CSCs characteristic(Figs. S1A and B). This evidence concerns the gene POU5F1 and renal cell carcinoma.