IL18 and polycystic ovary syndrome: Some studies have reported that PCOS is characterized by chronic inflammation and an increase in cytokines such as interleukin-1β, interleukin-1 receptor antagonist, interleukin-6, interleukin-17, interleukin-18, and other factors like fibroblast growth, vascular endothelial growth, and pigment epithelium-derived factor play pathophysiological roles in the development of PCOS (14).