Compared to the WT mice, the Borealin+/− mice exhibited positive enrichment in expressed genes involved in malignancy function (extracranial solid tumor and cancer), cytoskeletal and/or cytoplasmic functions (microtubule dynamics and organization of the cytoskeleton, filaments, and cytoplasm), viability (increased cell viability and decreased organismal death), and angiogenesis (Figure 5I). This evidence concerns the gene CDCA8 and cancer.