We found that Age, BMI, SBP, U.GLU, PRO, TP, GLB, ALT, and HDL.C were independent risk factors for progression from normal individuals to prediabetes, while Age, BMI, SBP, U.GLU, PRO, TG, and HDL.C were independent risk factors for progression from prediabetes to diabetes. This evidence concerns the gene GPT and diabetes mellitus.