Examining postoperative hormone level shifts in pituitary adenoma patients—owing to their significant physiological impact and potential to affect quality of life—primarily centered on serum prolactin, growth hormone, cortisol relief, adrenal cortical function recovery, thyroid function recovery, gonadal function recovery, and incidence of new-onset cortisol and thyroid deficiency following surgery. The gene discussed is GH1; the disease is hypothyroidism.