GP6 and atrial fibrillation: Interestingly, we found no difference in GPVI expression between anticoagulated and nonanticoagulated AF patients (Supplementary Fig. S1), a finding consistent with previous published research.14, 29This further highlights that patients with AF who are at risk of CES and have higher levels of circulating GPVI-dimer on their platelets could be a population of patients where GPVI inhibition may play a decisive role.