GPVI-dimer expression in patients with AF correlated to resting P-selectin exposure (r = 0.33,p = 0.004;Fig. 1D), whereas they did not in noAF patients (r = − 0.16,p = 0.40;Fig. 1D), indicating a unique relationship between GPVI-dimer formation and P-selectin exposure in AF patients' platelets. Here, SELP is linked to atrial fibrillation.