MCL1 and exocrine pancreatic carcinoma: In a pancreatic carcinoma study, it was found that the increased concentration of Tan IIA led to an increase in levels of Bax and Caspase-3, while the decrease of TCTP, Mcl-1, and Bcl-xL, thus inducing BxPC-3 cells cell apoptosis (Huang et al., 2013).