The AUC value of anti‐p53 Abs (0.702) was the highest among those of anti‐SOHLH1 Abs (0.581), CA19‐9 (0.570), anti‐FIRΔexon2 Abs (0.664), and CEA (0.677) in patients with CRC (Figure 3A). This evidence concerns the gene TP53 and colorectal carcinoma.