All these FGFR2 fusion/translocation CLC cases also displayed similar histopathological and immune subtypes: tumor cells showed small cuboids with a high nuclear/cytoplasmic ratio, oval nuclei, pale cytoplasm, and small atypia and were mostly in a well-differentiated state, with loose formation in the hyalinized collagen fibrous stroma characterized by angular small ducts, cords, or branching arrangements, no or few mucus secretions, MUC5ac negativity, MUC6 negativity or sporadic positivity, and CD56 positivity (Fig. 3A). The gene discussed is MUC5AC; the disease is neoplasm.