After T-cell adoptive transfer, CD40/CD40L interaction activates antigen-presenting cells (APC) via the NF-\documentclass[12pt]{minimal}\usepackage{amsmath}\usepackage{wasysym}\usepackage{amsfonts}\usepackage{amssymb}\usepackage{amsbsy}\usepackage{mathrsfs}\usepackage{upgreek}\setlength{\oddsidemargin}{-69pt}\begin{document}$$\kappa$$\end{document}B pathway, enhances the recruitment of immune effectors, and mobilizes endogenous tumor-recognizing T cells. The gene discussed is CD40LG; the disease is neoplasm.