LZTFL1 and respiratory failure: For rs10490770 located near LZTFL1 in the 3p21.31 region, it was in high LD with rs17713054 (D′ = 1), which was identified in COVID-19 GWASs as conferring a twofold increased risk of respiratory failure [5, 41, 50, 51] and an over twofold increased risk of mortality for individuals under 60 years old [52].