It is worth mentioning that the infiltration level of tumor-associated immunity, including T cells, neutrophils, macrophages, DC cells, Th1 cells, Th2 cells, T helper cells, and CD8 + T cells are significantly reduced in the GRID2IP-high group which points out that the high GRID2IP is mainly involved in the regulation of T-cell-dominated cellular immunity and macrophage-dominated innate immunity. The gene discussed is GRID2IP; the disease is neoplasm.