When analyzing the T cell subsets: CD4+ T cells and CD8+ T cells, or the ratio CD8+/CD4+, in MASH livers, as expected, there was a decrease in CD4+ T cells in favor of CD8+ cells, as clearly observed in Fig. 6c–e indicative of the chronic inflammatory state in male and female MASH livers. Here, CD4 is linked to metabolic dysfunction-associated steatohepatitis.