All assessed ECM components, collagen (p < 0.0001; η2 = 0.38), fibronectin (p < 0.0001; η2 = 0.34), versican (p = 0.013; η2 = 0.15), decorin (p = 0.028; η2 = 0.12), and TGF-β (p = 0.018; η2 = 0.14), had their expression influenced by COVID-19, except the elastic fibres (p = 0.271; η2 = 0.03). The gene discussed is TGFB1; the disease is COVID-19.