Moreover, we could not report long-term follow-up data for patients with IPF based on their PD-1/PD-L1 profile; yet, the goal of this work was to fuel future studies aiming to implement targeted therapies such as PD-1 inhibitors to patients with the appropriate endotype [6], as indicated by mediastinal lymph node profiling. The gene discussed is PDCD1; the disease is idiopathic pulmonary fibrosis.