However, since there are lung cancer patients with high PD-L1 expression who have a good postoperative course in clinical practice [13], while other lung cancer patients with low PD-L1 expression may show a poor postoperative course in clinical practice [14], factors related to tumor immunity other than PD-L1 may also have a significant impact on postoperative prognosis. This evidence concerns the gene CD274 and neoplasm.