ANKRD49 and cancer: Previously, we explored the expression pattern of ANKRD49 protein in NSCLC (80 cases of LUAD and 80 cases of LUSC) and found that the levels of ANKRD49 in cancer tissues were higher than those in tumor-adjacent normal tissues, its expression correlated with the TNM (tumor-node-metastasis) stage, distal metastasis, lymph node metastasis and differentiation [10].