NR4A2 and nervous system disorder: Li and colleagues measured the nuclear receptor related 1 protein (NURR1), a transcription factor important for maintaining dopaminergic neurons and regulating neuroinflammation, and cytokines levels in the peripheral blood mononuclear cells in a cohort of 312 PD patients, 318 healthy control and 332 non-PD neurological disease control (Li et al. 2018).