Intriguingly, the FGFR2 mRNA levels in PanCK(+) tumor epithelial cells at the EOCC tumor invasive margin were positively correlated with FGF20 mRNA levels in neighbor FAP(+) CAFs at the EOCC tumor invasive margin (Fig. 5f); while no correlations between FGFR2 and FGF20 were observed in LOCC tumor invasive margin (Fig. 5g). The gene discussed is FGF20; the disease is neoplasm.