Gene set enrichment analysis (GSEA) pathway analysis revealed that the complement system, WNT signaling, DNA replication, VEGFA-VEGFR2 signaling, and metabolic reprogramming were the top five ranked pathways in EPCAM(+) tumor epithelial cells of EOCC (Fig. 2d, Supplementary Table 8). This evidence concerns the gene KDR and neoplasm.