Relative analysis on mRNA expression revealed down regulations of GRM5 (33.33), GRM6 (3.13), GRM7 (3.85), GRIA1 (4.76), GRIN2A (4.76), GRIN2B (7.14) in the ADHD probands as compared to the controls (Fig. 4B). Here, GRIN2A is linked to attention deficit-hyperactivity disorder.