Among the 27 hub genes (ACTN2, TPM2, FLNC, MYH11, ITGA7, DMD, PAK3, LMOD1, GNAI1, MYLK, PLN, CTPS1, CNN1, MYH10, NLGN1, ADAMTSL3, MYOCD, MICU3, PPP1R14A, MAP2, OGN, PDE8B, RGS5, MAP1B, ITGA9, AKAP6, and SMTN) identified in this study, ACTN2, as pointed out earlier13, is a hub gene related to heart failure. The gene discussed is MYH10; the disease is heart failure.