Among the 27 hub genes (ACTN2, TPM2, FLNC, MYH11, ITGA7, DMD, PAK3, LMOD1, GNAI1, MYLK, PLN, CTPS1, CNN1, MYH10, NLGN1, ADAMTSL3, MYOCD, MICU3, PPP1R14A, MAP2, OGN, PDE8B, RGS5, MAP1B, ITGA9, AKAP6, and SMTN) identified in this study, ACTN2, as pointed out earlier13, is a hub gene related to heart failure. Here, PPP1R14A is linked to heart failure.