Finally, to explore the clinical relevance of SHN3, we investigated the prognostic value of SHN3, together with IL13Rα2, PTP1B and MMP9 in GBM and other cancers using the Betastasis (REMBRANDT), PRECOG and the Human Protein Atlas (HPA) databases. The gene discussed is PTPN1; the disease is glioblastoma.