Moreover, although the role of RKIP and BACH1 in altering one of the axes of cancer cell plasticity at a time—EMT, stemness, ferroptosis, metabolic switching—has been well studied, their ability to drive adaptation along multiple axes simultaneously due to the impact of ‘teams’ remains to be investigated experimentally, to further lend credence to our model predictions. The gene discussed is PEBP1; the disease is cancer.