A PubMed search was conducted from 01/01/2000 to 01/10/2023 with the following keywords: “menopause”, “symptoms”, “breast cancer”, “management”, “endocrine therapy”, “aromatase inhibitors”, “tamoxifen”, “vasomotor symptoms”, “arthralgia”, “sleeping disorders”, ”genitourinary symptoms”, “osteopenia”, “osteoporosis”, “hormone replacement therapy”, “non-hormonal treatments”, “SSRI”, “SNRI”, “clonidine”, “gabapentin” and “vaginal oestrogen. This evidence concerns the gene CYP19A1 and breast carcinoma.