HORMAD2 and Huntington disease: Reduced DNAm of a DMR within HORMAD2-AS1 was associated with circulating fT4 levels in a previous EWAS, and in our study, we identified reduced DNAm in cg03633435 within HORMAD2-AS1 in HD compared to GD in the discovery cohort and meta-analysis, again likely related to thyroid hormone levels (38).