PRPF19 and autism: Nevertheless, PRPF19WT and both PRPF19Gly404Ser and PPRF19Leu499Phe variants fully rescued the lethality in Prp19 pan-neural knockdown flies (Supplemental Figure 5A), allowing us to conduct the social space assay to further test the effect of these 2 de novo missense variants on social behavior related to the autism diagnosis in patients.