Etoposide is a well-known cytostatic drug, applied to combat a variety of different neoplasms by inducing DSBs in cells through the inhibition of topoisomerase II during replication.30 Cycling CD34+ cells treated with various concentrations of etoposide (1.5/5/10 μM) indicated different degrees of damage in a dose-dependent manner. The gene discussed is CD34; the disease is neoplasm.