PECAM1 and Sepsis: We demonstrated that elevated O-GlcNAc levels promoted the blood flow perfusion in the liver, mesentery, and lower limbs of the LPS induced septic mice, increased the expression of the vascular endothelial marker CD31 in the LPS induced septic mice aorta, indicating that O-GlcNAcylation might improve the prognosis of sepsis by influencing blood flow perfusion and vascular endothelial integrity.