Zuzga et al. [53] also found that rapid phosphorylation of VASP Ser157 and Ser239 could be induced by activation of the guanylyl cyclase C (GCC)/cGMP/protein kinase G (PKG) pathway; VASP Ser239 phosphorylation inhibits the biological behaviors of tumor cells. The gene discussed is GUCY2C; the disease is neoplasm.