While BMP-like leukemias harbored fusion products known to drive high HOXA cluster expression, including MLLT10, KMT2A, NUP214, and direct HOXA::TCR fusions, T-specified leukemias had fusions to ZFP36L2 (involved in cell cycle control during T-cell beta selection) and TLX1/3. This evidence concerns the gene NUP214 and leukemia.